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Molecule
Molecule

Precision Cancer Immunotherapy

Precision Cancer
Immuno
therapy

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Inspired by Nature’s Blueprint

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Uncovering Novel Therapeutic Targets

Through a deep dive into the symbiotic interplay between gut microbes and the immune system, we have uncovered a potent molecular mechanism, which we are leveraging to develop groundbreaking cancer immunotherapies.

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Leveraging Evolutionary Mechanisms

Through generational co-existence with microbes, human biology has evolved essential symbiotic biochemical pathways, which are crucial to protect us against many threats. At Adularia, we aim to tap into these mechanisms in order to treat cancer by enhancing the body’s natural immune response.

Scientific Insights

Tumor-targeted immunotherapy
Tumor-targeted immunotherapy
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Adularia provides an optimized molecule to leverage this mechanism, enabling the development of a tumor-targeted immunotherapy with improved target activation, and maximized efficacy.

A particular microbial metabolite activates tumor-residing macrophages, leading to cytokine release and a potent anti-tumor immune response

ACTIVATE

MEET THE TEAM

CEO & Co-Founder

Dr. Ana Montalban-Arques CEO Adularia

Dr. Ana Montalban-Arques

A scientist-entrepreneur dedicated to transforming cancer treatment through innovative immunotherapy solutions. With a strong background in tumor immunology...

COO & Co-Founder

​Dr. Philipp Busenhart COO Adularia

Dr. Philipp Busenhart

As a biotech executive with a strong background in oncology, pharmaceutical industry, and academic research, Philipp Busenhart brings a unique blend of scientific and industry expertise to Adularia...

CSO & Co-Founder

Dr. Eglė Katkevičiūtė CSO Adularia

Dr. Eglė Katkevičiūtė

A passionate scientist and entrepreneur with a PhD in Microbiology and Immunology from the University of Zurich. She also holds an integrated Master’s degree...

The Board of Directors

Drug Development

Dr. Terence Kelly

Dr. Terence Kelly

Dr. Terence A. Kelly is a seasoned pharmaceutical executive with over 30 years of experience in drug discovery and development across the U.S. and Europe. He began his career in 1990 as a medicinal chemist at Boehringer Ingelheim, contributing to projects in Immunology, Virology, CNS, and Cardiovascular diseases. From 2002 to 2009, he led the company's U.S. medicinal chemistry department, overseeing 145 scientists across various disciplines. In 2010, Dr. Kelly joined the neuroscience company CoMentis as Chief Scientific Officer, later becoming President and CEO. From 2019 to 2023 he served as President and CEO of Perception Neuroscience, a clinical-stage biotech company focused on mental health disorders. Dr. Kelly holds a B.S. in Chemistry from Rensselaer Polytechnic Institute, a Ph.D. in Chemistry from the University of Texas at Austin, and an MBA from New York University's Stern School of Business. He completed postdoctoral research in natural product synthesis at Yale University. Throughout his career, he has co-authored over 25 scientific publications and is an inventor on multiple patents. Currently, Dr. Kelly is the founder and President of Kelly Pharma Research Consulting, LLC, providing strategic and practical solutions in the drug discovery space. Dr. Kelly brings invaluable expertise to our team in advancing innovative healthcare solutions.

Clinical Trials

Prof. Alexander Knuth

Prof. Alexander Knuth

Professor Alexander Knuth, MD, is a medical oncologist and cancer immunologist with a distinguished career spanning several decades. He earned his medical degree from the Free University of Berlin in 1973 and completed his doctorate in pathology at the University of Zurich in 1974. His pioneering work in cancer immunology led to the discovery of multiple human cancer antigens, including MAGE, the first identified cancer/testis antigen, which has been a primary target in cancer vaccine development. From 2003 to 2013, Professor Knuth served as the Chair of Internal Medicine/Oncology at the University of Zurich, Switzerland. Following this, he was appointed as the Chief Executive Officer and Medical Director of the National Center for Cancer Care and Research at Hamad Medical Corporation in Doha, Qatar, a position he held until 2020. Throughout his career, Professor Knuth has been dedicated to advancing cancer immunotherapy, focusing on the development of peptide-based vaccines and adjuvants, establishing immune-monitoring techniques, and uncovering tumor escape mechanisms. His contributions have been recognized with numerous awards, including the prestigious Johann-Georg-Zimmermann Medal. Currently, as Professor Emeritus at the University of Zurich, Professor Knuth continues to contribute to the field of oncology through research and mentorship. His extensive clinical experience and groundbreaking research in cancer immunology make him an invaluable member of our team, guiding our efforts to develop innovative cancer therapies.

Science

​Prof. Michael Scharl

​Prof. Michael Scharl

Professor Michael Scharl, MD, is a distinguished gastroenterologist and researcher at the Department of Gastroenterology and Hepatology of the University Hospital Zurich, where he currently holds the position of Senior Attending Physician, heads the Translational Microbiome Research Center and acts as Vice Director of the Department. He is also Associate Professor for Gastroenterology and Hepatology with focus on Translational Microbiome Research at the University of Zurich. Professor Scharl's research focuses on understanding the complex interplay between genetic predispositions, intestinal microbiota, and immune responses in the development of intestinal inflammation, colorectal carcinoma and other malignancies. His work ultimately aims to improve the therapeutic options and quality of life of patients with gastrointestinal diseases. In recognition of his contributions to medical science, Professor Scharl has received multiple awards and is considered a leading expert in his field.

Advisors

Chairman

Dr. Ana Montalban-Arques CEO Adularia

Andrin Oswald, MD

Dr. Andrin Oswald, MD, is a distinguished pharmaceutical executive with extensive experience in global health initiatives and vaccine development. He earned his Doctor of Medicine from the University of Geneva in 1999. Dr. Oswald has held several key leadership positions throughout his career. He served as the Chief Executive Officer of Speedel Holding AG, which was later acquired by Novartis AG. At Novartis, he was the CEO and Division Head of Novartis Vaccines and Diagnostics from 2008 until its acquisition by GSK in 2015, and was a member of the executive committee. Following his tenure at Novartis, Dr. Oswald joined the Bill & Melinda Gates Foundation as the Director of Life Sciences Partnerships, overseeing the foundation's engagements with corporations. In 2020, he was appointed as the Chief Executive Officer of Centogene N.V., a company focused on rare diseases. In addition to his corporate roles, Dr. Oswald contributed to global health efforts as the Delegate for COVID-19 Vaccines and Immunotherapies for the Federal Government of Switzerland, advising on response and procurement strategies during the pandemic. Dr. Oswald's extensive experience in the pharmaceutical industry equip our team with world-class experience in pharmaceuticals and global health.

Board Member

Dr. Ana Montalban-Arques CEO Adularia

​Dr. Roman Fleck

Roman Fleck, PhD, MBA, is a seasoned biotechnology executive with over two decades of experience in pharmaceutical research, venture investment, and company leadership. He currently serves as the Chairman of the Board at Iktos, a company specializing in generative AI for drug discovery, as well as the Executive Chairman of HDAX Therapeutics, which focuses on neurological and cardiac diseases.. And until recently, he served as the Chairman of Omniose, a bacterial vaccine discovery company, Previously, Dr. Fleck was theCo-Founder and Chief Executive Officer of Janpix (aquired by Centessa Pharmaceuticals), an oncology-focused biotech company. He has also held roles as a Venture Advisor / Partner at Medicxi Ventures, where he invested in and represented companies on the boards of GlycoVaxyn (acquired by GSK), Versartis (NASDQ: VSAS), and Novocure (NASDQ: NVCR). He was also involved in Funxional Therapeutics (acquired by Boehringer Ingelheim) and Micromet (acquired by Amgen). Earlier in his career, Dr. Fleck led drug development projects in oncology, inflammation, and cardiovascular disease at Boehringer Ingelheim, advancing several compounds from pre-clinical to clinical stages. He earned his PhD in Organic Chemistry from the Massachusetts Institute of Technology (MIT) and an MBA from New York University's Stern School of Business.

​CEO & Co-Founder

Dr. Ana Montalban-Arques CEO Adularia

Dr. Ana Montalban-Arques

Dr. Ana Montalban-Arques is a scientist-entrepreneur dedicated to transforming cancer treatment through innovative immunotherapy solutions. With a strong background in tumor immunology, microbiome research, and translational medicine, she leads the development of cutting-edge therapies aimed at harnessing the body’s own defenses to fight cancer more effectively. She earned her PhD in Human Medicine from the Medical University of Graz (Austria) and holds a Master’s in Molecular Biology and Biotechnology as well as a Bachelor’s in Biology from the University of Murcia (Spain). Her scientific expertise spans oncology, immunotherapy, and host-microbiome interactions, laying the foundation for her pioneering work in biotech innovation. Prior to founding Adularia (formerly known as Recolony), Dr. Montalban-Arques held leadership and research positions at the University of Zurich, where she spearheaded projects in the Department of Gastroenterology and Hepatology, focusing on the interplay between cancer, microbiome, and the immune system. She also gained experience as a Postdoctoral Research Fellow at Hospital Universitario de La Princesa in Madrid, Spain. As the Co-Founder and CEO of Adularia, she drives the company’s vision to develop first-in-class tumor-targeted immunotherapies. Under her leadership, Adularia is advancing a novel small molecule therapy with the goal of enhancing treatment efficacy while minimizing side effects.
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“The development of novel immuno-oncology drugs will continue to revolutionize cancer therapies and bring new hope to patients. The team at Adularia is working on an exciting approach and has all the skills to succeed in this challenging field.”

Dr. T. Kelly

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SUPPORTERS & AWARDS

Our award-winning team and technology have thrived with the trust and support of numerous organizations. We are grateful for their invaluable contribution to our success.

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NEWS

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WHAT SETS US APART

Microbiome-based target identification

Novel immune-regulatory pathway for oncology

Tumor-targeted immunotherapy

Multi-omics guided selection of target population

AI-powered molecule design

Experienced team in Oncology, Immunology, and Drug Development

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